Principle Investigator:

Professor Zhongwen Xie, is a Wanjiang scholar and a doctoral supervisor in School of Tea and Food Science and Technology at Anhui Agricultural University.

He received a bachelor degree from East China Normal University in 1986, and PhD from Chinese Academy of Sciences in 1999. Previously, he was a post-doc fellow and senior scientist at the University of Kentucky in the United States. Currently he serves as an executive member of the national council of food nutrition and health..

Team members:

Prof. Daxiang Li

Prof. ‪Chi-Tang Ho, (Rutgers, USA)

Prof Weidong Yong, (Indiana, USA)

Prof. Dahua Chen

Prof. Shanming Ji

Dr. Hongyan Wang

Research interests:

1. Mechanism and effects of tea preventive metabolic syndrome.

2. Molecular mechanism of tea modulating circadian rhythm

3. Tea health products development.

Research grants:

1. Molecular mechanism of health effects and quality formation of characteristic compounds from Anhui tea resources (NSFC 2020-2023).

2. Functional evaluation and new products development of tea plus medical herbs. (2020-2022).

3. Evaluation and new products development of Anhui tea plant resource based on health benefits. 2017-2019).

4. Molecular Mechanism of EGCG Regulating Blood Pressure Circadian Rhyme in db/db mice (NSFC，2016-2019).

Selected publications

1. RNA-Sequencing Analysis Reveals l-Theanine Regulating Transcriptional Rhythm Alteration in Vascular Smooth Muscle Cells Induced by Dexamethasone. J Agric Food Chem. (IF=  4.192), 2019,67(19):5413-5422.

2. LC Domain-Mediated Coalescence Is Essential for Otu Enzymatic Activity to Extend Drosophila Lifespan. Mol Cell (IF= 15.584), 2019,74(2):363-377.e5

3. Dietary Supplement of Large Yellow Tea Ameliorates Metabolic Syndrome and Attenuates Hepatic Steatosis in db/db Mice. Nutrients (IF=4.546), 2018, 10, 75;

4. (-)-Epicatechin regulates blood lipids and attenuates hepatic steatosis in rats fed high-fat diet. Mol Nutr Food Res (IF=5.309), 2017, 61(11).

5. Smooth-muscle BMAL1 participates in blood pressure circadian rhythm regulation. Journal of Clinical Investigation (IF=13.765), 2015, 125(1), 324-3336.